These tests are not usually available at your doctors office, but your doctor can send the samples to a laboratory that can perform the tests. Methyl parathion 4 ec page 3 of 7 msds revision date ddmmyyyy. An initial decrease of 8 orders followed by 14 orders increase in adsorption is observed in moving from 10. The general population is probably not exposed to methyl parathion. Methyl parathion penncapm cancellation request 1099. Reports of methyl parathion intoxication, usually seen only in field pesticide applicators, have increased throughout the united states as a result of unauthorized application of methyl parathion inside homes. Parathion is extremely toxic from acute shortterm inhalation, oral, and dermal exposures. Find here list of methyl parathion cas no 298000, methyl parathion manufacturers, methyl parathion suppliers and exporters. Methyl parathion is not meant to be used inside buildings or homes.
Australia are required to produce a material safety data sheet. Material safety data sheet for methyl parathion, product number. Buy high purity methyl parathion analytical standards from chem service inc. Pocket guide to chemical hazards material type value methyl parathion cas twa 0. Cdc niosh pocket guide to chemical hazards methyl parathion. This product can kill you if swallowed even in small amounts.
Methyl parathion is an organophosphorus op insecticide with insecticidal properties derived from acetylcholinesterase ache inhibition. A chronicle of misuse and preventable human exposure. Material safety data sheet methyl acetate section 1 chemical product and company identification msds name. O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathion d 6. It is an organophosphate oxon, and the active metabolite of the insecticide parathion. Methyl parathion detection in vegetables and fruits using. More recent studies of water samples taken near where methyl parathion was. It was originally developed by ig farben in the 1940s. It may be attributed to more available binding sites and less steric hindrance of methyl parathion. Estimating solubility of parathion in organic solvents ilker polatoglu, y. Degradation is faster in the presence of sediments, and is faster in fresh water than in salt water. Poisoning with methyl parathion leads to cholinergic overstimulation with signs of toxicity including sweating, dizziness, vomiting, diarrhea. Acute exposure to parathion methyl may produce the following signs and symptoms.
Pharmacokinetics and pharmacodynamics of methyl parathion. India veritas house, 70 mint road, fort, mumbai 400 001. Parathion methyl d6 dimethyld 6 pestanal, analytical standard synonym. Op interim reregistration eligibility decisions ireds, therefore, are considered completed reds. Adsorption kinetics indicates that a good correlation exists between distribution coefficient kd and soil organic carbon. Mention of any company name or commercial product does not constitute endorsement by osha. Methyl parathion in drinkingwater world health organization. The first draft of methyl parathion in drinkingwater, background document for. Signs and symptoms of acute parathion methyl exposure. Methyl parathion is a brownish liquid that turns milky white. Methyl parathion is an acetylcholinesterase inhibitor, and excessive exposure can cause sweating, salivation, diarrhea, bradycardia, bronchoconstriction, muscle fasciculations, and coma. Page 9 of 31 parathion methyl specifications 2001 maximum.
It is highly toxic to nontarget organisms, including humans, so its use has been banned or restricted in most countries. Methyl parathion degrades rapidly in seawater, lake, and river waters, with 100% degradation occurring within 2 weeks to 1 month or more. Methyl parathion is a white crystalline solid which is often dissolved in a liquid solvent carrier. Paraoxon is one of the most potent acetylcholinesteraseinhibiting insecticides available, around 70% as potent as the nerve agent sarin, and so is now.
It is not allowed for sale and import in nearly all countries around the world, while a few allow it under subject to specified conditions only. Parathion, also called parathionethyl or diethyl parathion and locally clarification needed known as folidol, is an organophosphate insecticide and acaricide. Methyl parathion definition of methyl parathion by. Under certain exposure conditions, methyl parathion can affect the central nervous system resulting in dizziness, headache, difficulty breathing, vomiting, diarrhea, tremors, blurred vision, sweating. Parathion ec material safety data sheet villa crop. Methyl parathion coefficient of wateroil distribution. In extreme situations, for example when atmospheric conditions are dry. Aerial application of parathion ec may only be done by a registered aerial application operator using a. Pdf estimating solubility of parathion in organic solvents.
Physical and chemical properties of methyl parathion 23 s. Skin designation methyl parathion cas 298000 can be absorbed through the skin. Empirical formula hill notation c 8 d 6 h 4 no 5 ps. Vomiting, diarrhea, abdominal pain, seizures, and coma may also.
Methyl parathion penncapm cancellation request 1099 federal register. Mar 03, 2011 however, low levels of cholinesterase may be a result of methyl parathion exposure or it could be caused by factors other than methyl parathion. The results are graphically presented in figures figures1 1 and and2 2. Methyl parathion is an organophosphate op insecticide and acaricide, which is registered to control insect pests on food, feed and fiber crops. Parathion, also called parathion ethyl or diethyl parathion and locally known as folidol, is an organophosphate insecticide and acaricide.
O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathion d 6 empirical formula hill notation. It decomposes rapidly above 100 degrees c, creating an explosion hazard. The toxicity of organophosphate insecticides for nontarget organism has been the subject of extensive research for sustainable agriculture. Chemodynamics of methyl parathion and ethyl parathion. Methyl parathion represents the oldest generation of anticholinesterase insecticides that exhibit marked mammalian toxicity. Sampling and analytical methods methyl parathion partially. A meta description is an html tag in the html code of your website, which allows you to customize a section of text that describes the page itself. The health concerns of the use of methyl parathion have resulted in cancellation of its use in most food crops in the united states. It is a category i toxicant, and thus, is classified as a restricteduse. It may be found as a liquid or as a dry mixture where the liquid is absorbed onto a dry carrier. Methyl parathion synonyms, methyl parathion antonyms. The top countries of supplier is china, from which the percentage of methyl parathion supply is 100% respectively. Methyl parathion 4 ec page 4 of 7 msds revision date ddmmyyyy.
A wide variety of methyl parathion options are available to you, there are 9 suppliers who sells methyl parathion on, mainly located in asia. The central nervous system, blood, respiratory system, eyes, and skin are the organs most affected by acute exposure of humans to. Frl63878 methyl parathion, receipt of requests for cancellation. A different behavior is depicted by barren soil field samples for the removal of methyl parathion with change in concentration.
Methyl parathion is removed more efficiently by seven orders of magnitude than ethyl parathion. Methyl parathion contains 4 pounds of methyl parathion. October 27, 1999 volume 64, number 207 notices page 5787757881 from the federal register online via gpo access wais. Common name methyl parathion, parathion methyl, metaphos 4. P202 do not handle until all safety precautions have been read and understood. It is also used as an opthamological drug against glaucoma. Methyl parathion, sometimes called cotton poison, is a chemical pesticide that should be used only in open fields to control insects. These procedures were designed and tested for internal use by osha personnel. Methyl parathion is often detected in foods and air samples collected where methyl parathion is used. It plays a role in how your page is seen by search engine crawlers, and how it appears in serps. These methyl parathion manufacturing companies are providing good quality products at low prices. Source of sample, shell oil company, shell chemical division. Notice of receipt of a request to voluntarily amend methyl parathion pesticide registrations to terminate uses november 27, 2006 comment period closed on december 22, 2006 june 2, 2004 comment period closed on august 2, 2004.
The aim of this article is to identify the intermediate organic reaction products using a number of analytical techniques, such as uvvis, hplc, gcms and 1 h nmr. Substance name methyl parathion casrn 298000 last revised 03311987 298000 8056 hc azofos azophos bay 11405 bladanm dalf dimethylfenitrothion dimethyl 4nitrophenyl. O,odimethyld 6 o4nitrophenyl phosphorothioate, methyl parathiond 6 empirical formula hill notation. Parathion methyl, or methyl parathion, is an organophosphate insecticide, possessing an organothiophosphate group. Methyl parathions acute oral ld50 for male rats is almost identical to that of parathion, i. Any insect population may contain individuals naturally resistant to parathion ec and any other group code 1b insecticide. It is toxic by inhalation, ingestion and skin absorption. The resistant individuals can eventually dominate the insect population if these insecticides are used repeatedly. Identification of the substancemixture and of the companyundertaking product name. The effect of different ph 4, 7 and 10 on the adsorption of methyl parathion and ethyl parathion by different soil samples is studied. However, exposure to methyl parathion may occur at farms where it has been used as a pesticide. Contact with skin, i nhalation of dust or spray, or swallowing may be fatal.
Usually with the liquid solvent it is a combustible liquid. Methyl parathion manufacturers, methyl parathion suppliers. Note 2 the congelation temperature range should be nominated. Most commonly, it is used on cotton, soybean and vegetable fields. The technicalgrade methyl parathion smells like rotten eggs or garlic. The commercial product is a tan liquid xylene solution with a pungent odor. The present study is an attempt to estimate the residual concentration and to suggest remedial solution of adsorption by different types of. Parathion 56382 hazard summary exposure may occur from the use of parathion as an insecticide on agricultural crops. March 29, 2005 material safety data sheet section 1 product and company identification product identifier. Paraoxon is a synthetic aryl dialkyl phosphate compound and organophosphate acetylcholinesterase inhibitor that is the active metabolite of the insecticide parathion and is used as a pesticide. Parathion is a deep brown to yellow liquid with a faint odor of garlic. It is characterized as a reddishyellow oily liquid with a faint fruity odor, and exposure occurs by inhalation, ingestion, or contact. Methyl parathion is a pesticide that is used to kill insects on crops.
Methyl parathion definition is a highly toxic synthetic organophosphate insecticide c8h10no5ps. Epa i parathion is a compound, which inhibits cholinesterase enzyme activity in the nervous tissue. Methyl parathion is a brownish liquid that turns milky. Methyl parathion should not be heated above 55 degrees c. Page 9 of 31 parathionmethyl specifications 2001 maximum.
It is an organic phosphate insecticide which acts as an inhibitor of cholinesterase, and as such it is highly toxic by all routes of exposure. A significant first pass effect for methyl parathion is seen with. Methyl parathion is hydrolyzed by, and therefore not compatible with, alkaline materials. People who live close to areas of methyl parathion use also may be exposed to larger amounts of methyl parathion, because small amounts of the pesticide will move from the place where it is used to nearby areas. The photocatalytic degradation of o,odimethyl opnitrophenyl phosphorothioate common name methyl parathion in aqueous tio 2 suspensions is reported in this study. It is structurally very similar to parathion ethyl. Pakistan has banned the use of methylethyl parathions, but they are still illegally used. By the dermal route, methyl parathion is much less toxic than parathion, with an ld50 of 67 mgkg in rats of both sexes hayes 1963ex. The pharmacokinetics and pharmacodynamics of methyl parathion are complex, and the complexity varies with the route of exposure. Iupac name o, o dimethyl o4nitrophenyl phosphorothioate 3.